Description

4-(2,2,2-Trifluoroacetamido)Butanoic Acid is a high-purity trifluoroacetylated amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine group that is stable under various reaction conditions yet can be selectively deprotected, enabling complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating peptide mimetics and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially protease inhibitors and other small molecule therapeutics.
• Peptidomimetic Research: Used to incorporate non-natural amino acid residues into peptide chains to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and pesticides with fluorinated motifs for improved efficacy.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes and labeled compounds for studying enzyme mechanisms.
• Material Science: Can be utilized in the synthesis of specialized polymers and coatings where the introduction of fluorine atoms is desired for specific properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-(2,2,2-Trifluoroacetamido)Butanoic Acid
CAS No.	50632-83-2
Molecular Formula	C6H8F3NO3
Molecular Weight	199.13 g/mol
Synonyms	4-(Trifluoroacetamido)butyric Acid; 4-(2,2,2-Trifluoroacetamido)butanoic Acid; N-(3-Carboxypropyl)trifluoroacetamide; γ-(Trifluoroacetamido)butyric Acid; 4-(Trifluoroacetylamino)butanoic Acid; TFABA; TFA-GABA; Butanoic acid, 4-[(2,2,2-trifluoroacetyl)amino]-
EINECS	Contact for details

Quality Control

Every batch of 4-(2,2,2-Trifluoroacetamido)Butanoic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee specification adherence and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.