Description

(+)-2,3-o-Isopropylidene-L-Threitol CAS NO 50622-09-8 is a high-purity, chiral protected diol derivative of L-threitol, serving as a critical chiral building block and ligand precursor in advanced organic synthesis. Its value lies in its ability to impart stereochemical control in the synthesis of complex pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for research and production chemists in the pharmaceutical, fine chemical, and asymmetric catalysis industries who require reliable, high-quality chiral auxiliaries and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of antiviral drugs, nucleoside analogs, and other active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis: Used as a ligand precursor or backbone for constructing chiral catalysts and auxiliaries in enantioselective reactions.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Agrochemical Research: Serves as a building block for developing chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Material Science: Utilized in the development of chiral polymers and liquid crystals for advanced optical and electronic applications.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and stereochemistry research laboratories.

Basic Information

Product Name	(+)-2,3-o-Isopropylidene-L-Threitol
CAS No.	50622-09-8
Molecular Formula	C7H14O4
Molecular Weight	162.18 g/mol
Synonyms	(2R,3R)-2,3-O-Isopropylidene-1,2,3,4-butanetetrol; (2R,3R)-1,2,3,4-Butanetetrol 2,3-acetonide; L-Threitol 2,3-acetonide; (2R,3R)-2,3-Dihydroxybutane-1,4-diol 2,3-acetonide; (2R,3R)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol; (3R,4R)-3,4-Dihydroxy-1,2-O-isopropylidene-butane; Acetonide of L-Threitol
EINECS	Contact for details

Quality Control

Our (+)-2,3-o-Isopropylidene-L-Threitol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.