Description

Benzyl 2-Acetamido-2-Deoxy-4,6-o-Isopropylidene-B-D-Glucopyranoside is a protected glycosyl donor derivative, a key intermediate in sophisticated carbohydrate and glycoconjugate synthesis. Its value lies in providing a stable, reactive platform for constructing complex oligosaccharides and glycopeptides with precise stereochemistry. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycotherapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex glycopeptides, glycomimetics, and carbohydrate-based active pharmaceutical ingredients (APIs).
• Glycobiology Research: Used in academic and industrial R&D to study glycosylation pathways, enzyme mechanisms, and carbohydrate-protein interactions.
• Oligosaccharide Synthesis: Serves as a key glycosyl donor for the stepwise construction of biologically relevant oligosaccharides and polysaccharide fragments.
• Glycoconjugate Vaccine Development: Employed in the production of carbohydrate antigens for conjugate vaccine candidates targeting bacterial and viral pathogens.
• Chemical Biology Probes: Utilized to create labeled or tagged carbohydrate probes for cell surface imaging and biomarker discovery.
• Process Development: Acts as a standard or starting material for scaling up glycosylation reactions in process chemistry and pilot plant production.

Basic Information

Item	Details
Product Name	Benzyl 2-Acetamido-2-Deoxy-4,6-o-Isopropylidene-B-D-Glucopyranoside
CAS No.	50605-12-4
Molecular Formula	C18H25NO6
Molecular Weight	351.40 g/mol
Synonyms	Benzyl 2-Acetamido-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranoside; Benzyl 2-Acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside (common misnomer); 2-Acetamido-1-O-benzyl-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranose; N-Acetyl-1-O-benzyl-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranosylamine; β-D-Glucopyranoside, benzyl 2-(acetylamino)-2-deoxy-4,6-O-(1-methylethylidene)-; Benzyl N-acetyl-4,6-O-isopropylidene-β-D-glucosaminide
EINECS	Contact for details

Quality Control

Our Benzyl 2-Acetamido-2-Deoxy-4,6-o-Isopropylidene-B-D-Glucopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	-30° to -40° (c=1 in CHCl₃)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.