Description

3-Iodo-4-Methoxytoluene is a versatile halogenated aromatic compound, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both iodine and methoxy substituents, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for applications in cross-coupling reactions and the development of active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where specific halogen substitution patterns are required for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of novel organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Heck couplings to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways.
• Dye and Pigment Intermediate: Used in the synthesis of complex dyes and organic pigments where iodine incorporation alters light absorption properties.

Basic Information

Product Name	3-Iodo-4-Methoxytoluene
CAS No.	50597-88-1
Molecular Formula	C8H9IO
Molecular Weight	248.06 g/mol
Synonyms	1-Iodo-2-Methoxy-5-Methylbenzene; 2-Iodo-5-Methylanisole; 4-Methoxy-3-Iodotoluene; 3-Iodo-4-Methylanisole; 5-Methyl-2-Iodoanisole; 2-Methoxy-5-Methyl-1-Iodobenzene; 3-Iodo-p-Cresyl Methyl Ether
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Methoxytoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.