Description

(+/-)-1,1'-Binaphthyl-2,2'-Diyl Hydrogen Phosphate CAS NO 50574-52-2 is a chiral phosphoric acid derivative widely recognized as a versatile organocatalyst and resolving agent. Its primary value lies in its ability to facilitate highly enantioselective transformations, making it indispensable for the synthesis of optically active compounds. This product is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and fine chemical industries where precise stereochemical control is paramount.

Application

• Asymmetric Organocatalysis: Employed as a Brønsted acid catalyst for a wide range of enantioselective reactions, including Friedel-Crafts alkylations, transfer hydrogenations, and Mannich reactions.
• Chiral Resolution: Used to separate racemic mixtures of amines, alcohols, and other chiral compounds through diastereomeric salt formation.
• Pharmaceutical Intermediate Synthesis: A key building block and catalyst in the multi-step synthesis of active pharmaceutical ingredients (APIs) requiring specific chirality.
• Ligand Precursor: Serves as a starting material for the synthesis of more complex chiral ligands used in metal-catalyzed asymmetric synthesis.
• Material Science Research: Investigated for the development of chiral stationary phases (CSPs) in chromatography and chiral molecular recognition systems.
• Agrochemical Development: Applied in the research and production of enantiomerically pure herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	(+/-)-1,1'-Binaphthyl-2,2'-Diyl Hydrogen Phosphate
CAS No.	50574-52-2
Molecular Formula	C₂₀H₁₃O₄P
Molecular Weight	348.29 g/mol
Synonyms	1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate; BINOL phosphate; Racemic BINOL phosphate; (±)-1,1'-Bi-2-naphthol hydrogen phosphate; 2,2'-Dihydroxy-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate; BINAP acid; BINOL phosphoric acid; 50574-52-2
EINECS	Contact for details

Quality Control

Our (+/-)-1,1'-Binaphthyl-2,2'-Diyl Hydrogen Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for catalytic and synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.