Description

4-Chloro-1-(2,4-Difluorophenyl)Butan-1-One is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its value lies in its precise molecular structure, which serves as a critical intermediate for constructing more complex active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the difluorophenyl moiety for enhanced biological activity and stability.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals where fluorinated aromatic units are required for specific electronic or thermal properties.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation and subsequent functional group transformations to introduce complex fluorinated ketone structures.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	4-Chloro-1-(2,4-Difluorophenyl)Butan-1-One
CAS No.	50528-16-0
Molecular Formula	C10H9ClF2O
Molecular Weight	218.63 g/mol
Synonyms	1-(2,4-Difluorophenyl)-4-chlorobutan-1-one; 4-Chloro-1-(2,4-difluorophenyl)-1-butanone; 4-Chloro-2',4'-difluorobutyrophenone; γ-Chloro-2,4-difluorobutyrophenone; Butan-1-one, 4-chloro-1-(2,4-difluorophenyl)-; 50528-16-0; 2,4-Difluorophenyl 4-chlorobutyl ketone
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(2,4-Difluorophenyl)Butan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.