Description

5-Chloro-3-Methylbenzo[B]Thiophene-2-Carbaldehyde is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its functionalized benzothiophene scaffold, which serves as a critical precursor for developing novel pharmaceuticals and functional materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a building block for organic semiconductors, non-linear optical (NLO) materials, and advanced polymers due to its electron-rich thiophene core.
• Chemical Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as an aldehyde component in condensation reactions to form more complex heterocycles.
• Ligand and Catalyst Development: Utilized to create novel chelating ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	5-Chloro-3-Methylbenzo[B]Thiophene-2-Carbaldehyde
CAS No.	50451-78-0
Molecular Formula	C10H7ClOS
Molecular Weight	210.68 g/mol
Synonyms	5-Chloro-3-methyl-1-benzothiophene-2-carboxaldehyde; 5-Chloro-3-methylbenzo[b]thiophene-2-carboxaldehyde; 2-Formyl-5-chloro-3-methylbenzo[b]thiophene; 5-Chloro-3-methyl-2-benzothiophenecarboxaldehyde; 5-Chloro-3-methylbenzo[b]thiophene-2-carbaldehyde; 5-Chloro-3-methyl-1-benzothiophene-2-carbaldehyde; 3-Methyl-5-chlorobenzo[b]thiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Methylbenzo[B]Thiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.