Description

Methyl 2-Formyl-3-Oxo-Propionate is a versatile and highly reactive keto-ester building block, essential for advanced organic synthesis. Its bifunctional nature, featuring both a formyl and a keto-ester group, makes it a critical intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds like pyrazoles, isoxazoles, and pyrroles.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific keto-ester functionalities.
• Fine Chemical Building Block: Serves as a versatile starting material for synthesizing complex molecules in flavors, fragrances, and specialty polymers.
• Academic & Industrial Research: Employed in method development and novel reaction pathways, including cyclocondensation and multi-component reactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymeric materials with tailored properties.

Basic Information

Product Name	Methyl 2-Formyl-3-Oxo-Propionate
CAS No.	50427-65-1
Molecular Formula	C5H6O4
Molecular Weight	130.10 g/mol
Synonyms	Methyl 3-Oxo-2-formylpropanoate; Methyl 2-Formyl-3-oxopropanoate; 2-Formyl-3-oxopropionic Acid Methyl Ester; 3-Oxo-2-formylpropionic Acid Methyl Ester; Methyl Oxalylacetate Aldehyde; Methyl 2-Formylmalonate Semialdehyde; Oxo(Formyl)Propionic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Formyl-3-Oxo-Propionate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C to minimize degradation. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.