Description

(3E,6R,9E,11R,14R)-11-Hydroxy-6,14-Dimethyl-1,7-Dioxacyclotetradeca-3,9-Diene-2,8-Dione is a complex macrolide compound with a defined stereochemistry, offering a high-purity building block for advanced chemical synthesis. Its precise molecular architecture makes it a valuable intermediate for research and development in specialized pharmaceutical and fine chemical applications. This compound is essential for scientists and manufacturers working on novel active pharmaceutical ingredients (APIs), complex natural product analogs, and chiral catalysts.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel macrolide antibiotics and other therapeutic agents.
• Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex natural product analogs and specialty molecules.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Catalyst Development: Potential precursor or ligand in the development of asymmetric catalysts for enantioselective synthesis.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(3E,6R,9E,11R,14R)-11-Hydroxy-6,14-Dimethyl-1,7-Dioxacyclotetradeca-3,9-Diene-2,8-Dione
CAS No.	50376-41-5
Molecular Formula	C15H22O5
Molecular Weight	282.33 g/mol
Synonyms	11-Hydroxy-6,14-dimethyl-1,7-dioxacyclotetradeca-3,9-diene-2,8-dione; (3E,6R,9E,11R,14R)-form; (3E,6R,9E,11R,14R)-11-Hydroxy-6,14-dimethyl-1,7-dioxacyclotetradeca-3,9-diene-2,8-dione; 6,14-Dimethyl-11-hydroxy-1,7-dioxacyclotetradeca-3,9-diene-2,8-dione; Macrolide intermediate 50376-41-5; (3E,6R,9E,11R,14R)-11-Hydroxy-6,14-dimethyloxacyclotetradeca-3,9-diene-2,8-dione
EINECS	Contact for details

Quality Control

Our (3E,6R,9E,11R,14R)-11-Hydroxy-6,14-Dimethyl-1,7-Dioxacyclotetradeca-3,9-Diene-2,8-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.