Description

Caindexname:8-Azabicyclo[3.2.1]Octane-2-Carboxylic is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in the fields of neurology and virology. It is an essential building block for research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents. The product is supplied as a fine white to off-white powder, meeting the stringent quality requirements for modern pharmaceutical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, including tropane alkaloid derivatives.
• Neurological Research: Serves as a precursor for compounds targeting neurotransmitter systems, useful in the development of treatments for CNS disorders.
• Antiviral Drug Development: Used in the research and production of novel antiviral agents due to its constrained bicyclic scaffold.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective chemical reactions to create enantiomerically pure compounds.
• Medicinal Chemistry R&D: A valuable scaffold for constructing diverse chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for GMP-scale production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Caindexname:8-Azabicyclo[3.2.1]Octane-2-Carboxylic
CAS No.	50372-80-0
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	8-Azabicyclo[3.2.1]octane-2-carboxylic acid; 2-Carboxy-8-azabicyclo[3.2.1]octane; Nortropane-2-carboxylic acid; 8-Azanorbornane-2-carboxylic acid; 2-Nortropic acid; Endo-Nortropine-2-carboxylic acid; (1R,2S,5S)-8-Azabicyclo[3.2.1]octane-2-carboxylic acid (for specific enantiomer); Tropane-2-carboxylic acid, 8-aza- (8CI)
EINECS	Contact for details

Quality Control

Our Caindexname:8-Azabicyclo[3.2.1]Octane-2-Carboxylic is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, purity, and impurity profiles. Our quality commitment aligns with ICH guidelines, and we can support development projects requiring GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.