Description

Cucurbitacin J is a highly bioactive triterpenoid compound belonging to the cucurbitacin family, known for its potent pharmacological properties. Its primary value lies in its significant anti-inflammatory and anti-cancer activities, making it a crucial reference standard and research chemical for drug discovery and development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who are investigating novel therapeutic agents and signaling pathways.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of anti-cancer and anti-inflammatory drugs.
• Biochemical Studies: Used as a potent inhibitor to study JAK/STAT and other cellular signaling pathways involved in proliferation and apoptosis.
• Academic Research: Employed in university and institutional labs for in vitro and in vivo studies on its cytotoxic effects against various cancer cell lines.
• Natural Product Isolation & Analysis: Acts as a qualitative and quantitative marker in the HPLC analysis of plant extracts from the Cucurbitaceae family.
• Preclinical Studies: Utilized in animal model research to evaluate pharmacokinetics, efficacy, and toxicity profiles of cucurbitacin-based therapies.

Basic Information

Product Name	Cucurbitacin J
CAS No.	5979-41-9
Molecular Formula	C₃₂H₄₆O₈
Molecular Weight	558.71 g/mol
Synonyms	Jasminin; Cucurbitacin J (Jasminin); 23,24-Dihydrocucurbitacin F; 23,24-Dihydro-10α-cucurbitacin F; (23S)-23,24-Dihydrocucurbitacin F; (23S)-23,24-Dihydro-10α-cucurbitacin F; 3β,16α,20β,25-Tetrahydroxy-10α-cucurbita-5,23-dien-11-one
EINECS	Contact for details

Quality Control

Our Cucurbitacin J is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.