Description

B-Sulfopropionicanhydride is a specialized sulfonic acid anhydride derivative, a key reactive intermediate in advanced organic synthesis. Its primary value lies in its ability to act as a versatile sulfopropionylating agent, facilitating the introduction of the sulfopropionic acid moiety into target molecules under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs), functional polymers, and specialty surfactants.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing sulfonated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Polymer Modification: Used to introduce sulfonic acid groups into polymer backbones, enhancing properties like hydrophilicity and ion-exchange capacity for membrane and resin production.
• Surfactant Synthesis: Serves as a precursor for creating anionic surfactants with specific chain lengths and properties for specialized detergents and emulsifiers.
• Bioconjugation Chemistry: Employed in the derivatization of biomolecules (e.g., peptides, proteins) to alter solubility or introduce functional handles for further modification.
• Ligand and Catalyst Development: Useful in the preparation of sulfonated ligands for metal complexes used in homogeneous catalysis.
• Material Science Research: Applied in the surface functionalization of nanomaterials and the creation of novel ionic liquids or electrolytes.

Basic Information

Product Name	B-Sulfopropionicanhydride
CAS No.	5961-88-6
Molecular Formula	C6H8O5S
Molecular Weight	192.19 g/mol
Synonyms	3-Sulfopropionic Anhydride; 1,3-Propanesultone-2,4-dione; β-Sulfopropionic Anhydride; 3-Oxo-1,3-oxathiolane-2,4-dione 1,1-dioxide; Sulfopropanoic Anhydride; Propionic acid, 3-sulfo-, cyclic anhydride; NSC 163022
EINECS	227-760-6

Quality Control

Every batch of B-Sulfopropionicanhydride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as identity, purity, and impurity profiles. Our quality protocols are designed to support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its reactivity as a strong acid derivative, it should be kept separate from bases, oxidizing agents, and moisture. Use appropriate corrosion-resistant containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.