Description

(5R)-4,5,5Aα,6,7,8-Hexahydro-8α-Hydroxy-7α-Methyl-5-Isopropyl-3H-Naphtho[1,8-Bc]Furan-3-One is a high-purity, stereochemically defined organic compound with a complex fused-ring structure. This compound serves as a critical chiral intermediate in advanced organic synthesis, particularly for the development of complex natural products and active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, especially in steroid-like or terpenoid-based therapeutic agents.
• Agrochemical Research: Used in the development of novel, high-specificity pesticides and herbicides that leverage its unique polycyclic structure.
• Fine Chemical Synthesis: Employed as a sophisticated precursor in the multi-step synthesis of specialty chemicals, flavors, and fragrances.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry, including asymmetric synthesis and catalysis research.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or advanced polymeric materials with specific stereochemical properties.

Basic Information

Product Name	(5R)-4,5,5Aα,6,7,8-Hexahydro-8α-Hydroxy-7α-Methyl-5-Isopropyl-3H-Naphtho[1,8-Bc]Furan-3-One
CAS No.	5956-13-8
Molecular Formula	C₁₆H₂₂O₃
Molecular Weight	262.34 g/mol
Synonyms	(5R)-8α-Hydroxy-7α-methyl-5-(1-methylethyl)-4,5,5aα,6,7,8-hexahydro-3H-naphtho[1,8-bc]furan-3-one; 8α-Hydroxy-7α-methyl-5-(propan-2-yl)-4,5,5aα,6,7,8-hexahydro-3H-naphtho[1,8-bc]furan-3-one; 5-Isopropyl-8α-hydroxy-7α-methyl-4,5,5aα,6,7,8-hexahydro-3H-naphtho[1,8-bc]furan-3-one; (5R)-8α-Hydroxy-7α-methyl-5-isopropylperhydro-3H-naphtho[1,8-bc]furan-3-one; 5956-13-8; Naphtho[1,8-bc]furan-3-one derivative
EINECS	Contact for details

Quality Control

Our (5R)-4,5,5Aα,6,7,8-Hexahydro-8α-Hydroxy-7α-Methyl-5-Isopropyl-3H-Naphtho[1,8-Bc]Furan-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.