Description

(R)-(+)-N,α-Dimethylbenzylamine is a high-purity chiral amine building block and resolving agent of significant commercial and research importance. Its primary value lies in its utility as a versatile chiral auxiliary for the asymmetric synthesis of pharmaceutical intermediates and fine chemicals. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors requiring enantiomerically pure products.

Application

• Chiral Resolution Agent: Widely used for the optical resolution of racemic acids via diastereomeric salt formation.
• Asymmetric Synthesis: Serves as a key chiral auxiliary and ligand in catalytic asymmetric reactions, including hydrogenations and alkylations.
• Pharmaceutical Intermediate: Critical building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Catalyst Preparation: Employed in the synthesis of chiral catalysts and organocatalysts for fine chemical production.
• Research & Development: A standard reagent in academic and industrial R&D for developing new stereoselective methodologies.

Basic Information

Product Name	(R)-(+)-N,α-Dimethylbenzylamine
CAS No.	5933-40-4
Molecular Formula	C9H13N
Molecular Weight	135.21 g/mol
Synonyms	(R)-(+)-α-Methylbenzylmethylamine; (R)-1-Phenylethylmethylamine; (R)-N-Methyl-1-phenylethylamine; (R)-N-Methyl-α-methylbenzylamine; Dextro-N-Methyl-α-methylbenzylamine; (R)-N,α-Dimethylbenzylamine; (R)-(+)-N-Methyl-1-phenylethylamine; (R)-1-Phenyl-N-methylethylamine
EINECS	227-675-0

Quality Control

Our (R)-(+)-N,α-Dimethylbenzylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (e.e.), and impurity profiles. We adhere to relevant industry standards and can provide material suitable for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its basic nature, ensure containers are kept tightly sealed to prevent absorption of atmospheric carbon dioxide.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (e.e.) (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation [α]D20	+30.0° to +33.0° (c=1 in ethanol)
Refractive Index nD20	1.520 - 1.525
Density (20°C)	0.930 - 0.940 g/mL
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.