Description

(R)-(-)-Benzoin CAS NO 5928-66-5 is a high-purity, single-enantiomer chiral compound belonging to the α-hydroxy ketone class. This optically active intermediate is critical for synthesizing pharmaceuticals and fine chemicals where stereochemistry dictates biological activity and material properties. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors requiring precise molecular chirality.

Application

• Pharmaceutical Intermediate: A key chiral building block for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs and other therapeutics.
• Asymmetric Synthesis Catalyst/Chiral Ligand: Used in the preparation of chiral catalysts and ligands for enantioselective reactions, such as asymmetric hydrogenation and carbon-carbon bond formation.
• Agrochemical Synthesis: Serves as a precursor for developing chiral pesticides and herbicides, where the specific enantiomer can offer improved efficacy and reduced environmental impact.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require a specific handedness for their functional properties.
• Academic & Industrial Research: A valuable standard and starting material in organic chemistry research for method development and studying stereoselective transformations.
• Polymer Chemistry: Can be utilized as a monomer or initiator in the synthesis of chiral polymers with potential applications in optics and electronics.

Basic Information

Product Name	(R)-(-)-Benzoin
CAS No.	5928-66-5
Molecular Formula	C14H12O2
Molecular Weight	212.24 g/mol
Synonyms	(R)-(-)-2-Hydroxy-1,2-diphenylethanone; (R)-Benzoin; (R)-2-Hydroxy-2-phenylacetophenone; D-(-)-Benzoin; (R)-α-Hydroxybenzyl Phenyl Ketone; (R)-1,2-Diphenyl-2-hydroxyethanone; (-)-Benzoin; R-Benzoin
EINECS	227-668-1

Quality Control

Our (R)-(-)-Benzoin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets stringent specifications for enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and optical rotation are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Optical Rotation [α]D20	-115° to -125° (c=1 in ethanol)
Melting Point	132°C - 136°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.