Description

Trt-Gly-Oh CAS NO 5893-05-0 is a protected amino acid derivative, specifically N-(tert-Butoxycarbonyl)-glycine, widely used as a crucial building block in peptide synthesis. This compound is essential for pharmaceutical research and development, enabling the controlled construction of complex peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Boc-protected amino acid for the sequential assembly of peptides.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for producing custom peptides and peptide fragments.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of peptide-based drugs and APIs.
• Bioconjugation: Employed to introduce glycine linkers or spacers in the modification of proteins, antibodies, and other biomolecules.
• Research & Development: A standard reagent in academic and industrial R&D labs for exploring new peptide structures and biological activities.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.

Basic Information

Product Name	Trt-Gly-Oh CAS NO 5893-05-0
CAS No.	5893-05-0
Molecular Formula	C7H13NO4
Molecular Weight	175.18 g/mol
Synonyms	N-(tert-Butoxycarbonyl)glycine; Boc-Gly-OH; Boc-Glycine; (tert-Butoxycarbonyl)aminoacetic acid; 2-[(2-Methylpropan-2-yl)oxycarbonylamino]acetic acid; N-Boc-glycine; BOC-Gly; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	227-561-6

Quality Control

Our Trt-Gly-Oh is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency suitable for sensitive applications like pharmaceutical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation	[α]20/D: N/A (achiral)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.