Description

2-Ethynylcyclohexanol is a versatile alicyclic compound featuring both an ethynyl and a hydroxyl functional group, making it a valuable building block in advanced organic synthesis. Its unique structure provides a reactive handle for click chemistry and other coupling reactions, enabling the construction of complex molecular architectures. This intermediate is particularly sought after by research and development teams in the pharmaceutical and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and advanced materials with tailored properties.
• Click Chemistry: The terminal alkyne group makes it an ideal participant in Huisgen cycloaddition (copper-catalyzed azide-alkyne cycloaddition) reactions for bioconjugation and material surface functionalization.
• Ligand & Catalyst Development: Employed in the preparation of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Fragrance & Flavor Chemistry: Acts as a precursor for the synthesis of specific aroma chemicals and flavoring substances.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Product Name	2-Ethynylcyclohexanol
CAS No.	5877-41-8
Molecular Formula	C8H12O
Molecular Weight	124.18 g/mol
Synonyms	2-Ethynylcyclohexan-1-ol; 1-Hydroxy-2-ethynylcyclohexane; Cyclohexanol, 2-ethynyl-; 2-Ethynyl-1-cyclohexanol; 2-Ethynylcyclohexyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Ethynylcyclohexanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to prevent potential oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.