Description

2-Thioxotetrahydro-1,3-Oxazole is a versatile heterocyclic building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the preparation of various pharmacologically active molecules and specialty chemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of thiazolidinone and rhodanine derivatives, which are core structures in drug discovery for antimicrobial, antiviral, and antidiabetic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its reactive thione and cyclic structure.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and functional materials requiring specific heterocyclic frameworks.
• Bioconjugation & Chemical Biology: Employed in the modification of peptides and proteins due to its ability to react selectively with amines and other functional groups.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	2-Thioxotetrahydro-1,3-Oxazole
CAS No.	5840-81-3
Molecular Formula	C3H5NOS
Molecular Weight	103.14 g/mol
Synonyms	2-Thioxooxazolidine; 2-Oxazolidinethione; Rhodanine, tetrahydro-; 2-Thioxo-1,3-oxazolidine; 2-Mercaptooxazolidine; 2-Thioxooxazolidin-4-one (tautomer); NSC 401122; Tetrahydro-2-thioxo-1,3-oxazole
EINECS	227-420-7

Quality Control

Our 2-Thioxotetrahydro-1,3-Oxazole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.