Description

5-(Iodomethyl)-2-Pyrrolidinone is a versatile heterocyclic building block featuring a reactive iodomethyl group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of N-methyl-D-aspartate (NMDA) receptor antagonists and other neurologically active compounds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive site for structural diversification.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes and labeled compounds due to the iodine atom's potential for further functionalization or as a leaving group.
• Polymer & Material Science: Employed in the synthesis of functionalized polymers and advanced materials where the pyrrolidinone ring contributes specific physicochemical properties.
• Organic Synthesis Reagent: Acts as an alkylating agent in various C-C and C-N bond-forming reactions to introduce the 2-pyrrolidinone moiety into target molecules.

Basic Information

Product Name	5-(Iodomethyl)-2-Pyrrolidinone
CAS No.	5831-75-4
Molecular Formula	C5H8INO
Molecular Weight	225.03 g/mol
Synonyms	1-(Iodomethyl)-2-pyrrolidinone; 2-Pyrrolidinone, 5-(iodomethyl)-; 5-Iodomethyl-2-pyrrolidinone; 1-Iodomethyl-2-pyrrolidinone; 5-(Iodomethyl)pyrrolidin-2-one; NSC 163184; 2-Oxopyrrolidine-5-methyl iodide
EINECS	Contact for details

Quality Control

Our 5-(Iodomethyl)-2-Pyrrolidinone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.