Description

Caffeine Hydrobromide is a water-soluble salt form of caffeine, offering enhanced stability and bioavailability for specialized applications. This compound is valued for its precise pharmacological activity and consistent performance in controlled formulations. It is primarily utilized by the pharmaceutical and nutraceutical industries for research, analytical standards, and the development of therapeutic and performance-enhancing products.

Application

• Pharmaceutical Intermediates: Serves as a key precursor or active ingredient in the synthesis of specialized central nervous system stimulants and analeptic agents.
• Analytical Reference Standards: Used as a high-purity calibrant in HPLC, GC, and spectrophotometric methods for quality control in drug and supplement manufacturing.
• Biochemical Research: Employed in laboratory studies to investigate adenosine receptor antagonism, neurological pathways, and metabolic effects.
• Nutraceutical Formulations: Incorporated into advanced dietary supplements and performance blends where a highly soluble and stable caffeine source is required.
• Veterinary Medicine: Applied in formulations for respiratory and cardiac stimulation in certain animal health products.

Basic Information

Product Name	Caffeine Hydrobromide
CAS No.	5743-18-0
Molecular Formula	C8H10BrN4O2
Molecular Weight	259.10 g/mol
Synonyms	1,3,7-Trimethylxanthine hydrobromide; Caffeine HBr; Theine hydrobromide; Guaranine hydrobromide; Methyltheobromine hydrobromide; 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione hydrobromide
EINECS	227-263-7

Quality Control

Our Caffeine Hydrobromide is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and research applications. Comprehensive testing includes identification, assay, and impurity profile analysis. A Certificate of Analysis (COA) documenting purity, residual solvents, and heavy metals is provided with every shipment to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.