Description

2,2-Dimethyl-1,3-Dioxolane-4-Carboxaldehyde is a versatile and highly reactive aldehyde derivative of a protected glycerol. This compound is a crucial chiral synthon and building block in organic synthesis, prized for its ability to introduce functionalized glyceraldehyde units into complex molecules. It is primarily sought after by research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active ingredients and specialty compounds.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of nucleoside analogs, antiviral drugs, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used as a building block for creating chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and advanced materials requiring specific stereochemistry.
• Academic & Industrial Research: Serves as a standard reagent in methodological development for asymmetric synthesis and carbohydrate chemistry.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent for producing specialty polymers with tailored properties.

Basic Information

Product Name	2,2-Dimethyl-1,3-Dioxolane-4-Carboxaldehyde
CAS No.	5736-03-8
Molecular Formula	C6H10O3
Molecular Weight	130.14 g/mol
Synonyms	(R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde; (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde; D-Glyceraldehyde Acetonide; L-Glyceraldehyde Acetonide; Isopropylidene Glyceraldehyde; 2,2-Dimethyl-4-formyl-1,3-dioxolane; 4-Formyl-2,2-dimethyl-1,3-dioxolane; Acetonide-protected Glyceraldehyde
EINECS	227-270-7

Quality Control

We supply 2,2-Dimethyl-1,3-Dioxolane-4-Carboxaldehyde in various purity grades, including standard and high-purity enantiomers, to meet diverse application needs. Our products undergo rigorous quality testing to ensure compliance with industry standards, including identity confirmation, chiral purity (enantiomeric excess), and chemical purity assays. A comprehensive Certificate of Analysis (COA) detailing specifications and test results is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is easily oxidized; for long-term storage of larger quantities, consideration should be given to maintaining an inert atmosphere (e.g., under nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee (for specified enantiomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.