Description

4-Acetyl-4'-Bromobiphenyl is a high-purity brominated biphenyl derivative, serving as a versatile and critical organic intermediate for advanced synthesis. Its molecular structure, featuring both acetyl and bromo functional groups, makes it an essential building block for constructing complex molecules in pharmaceutical and materials science research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and liquid crystal industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its biphenyl core for bioactive molecule design.
• Liquid Crystal Materials: Serves as a fundamental building block for creating bromine-substituted liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for synthesizing electron-transport or host materials in OLED device fabrication.
• Polymer Chemistry: Utilized as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and optical properties.
• Academic & Industrial Research: A valuable reagent for methodological studies in cross-coupling reactions (e.g., Suzuki, Stille) and other catalytic transformations.

Basic Information

Product Name	4-Acetyl-4'-Bromobiphenyl
CAS No.	5731-01-1
Molecular Formula	C14H11BrO
Molecular Weight	275.14 g/mol
Synonyms	1-(4'-Bromo[1,1'-biphenyl]-4-yl)ethanone; 4'-Bromo-4-acetylbiphenyl; p-Bromophenyl 4-acetylphenyl ketone; 4-Acetyl-4'-bromodiphenyl; (4-Bromophenyl)(4-acetylphenyl)methanone; 4-Bromo-4'-acetylbiphenyl; 1-[4-(4-Bromophenyl)phenyl]ethanone
EINECS	227-246-8

Quality Control

Every batch of 4-Acetyl-4'-Bromobiphenyl is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure the material meets the precise requirements of research and production. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment. Our quality commitment supports compliance with cGMP and ISO 9001 standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.