Description

2-Methylpropanal Trimethylene Acetal is a specialized acetal derivative of isobutyraldehyde, serving as a versatile protecting group and synthetic intermediate in advanced organic synthesis. Its primary value lies in its ability to mask the reactive aldehyde functionality under a wide range of reaction conditions, enabling complex multi-step transformations. This high-purity building block is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, where precise control over molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Used in the multi-step synthesis of active pharmaceutical ingredients (APIs) where selective aldehyde protection is required.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and advanced materials requiring specific acetal functionalities.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and catalysis studies.
• Polymer Chemistry: Can be utilized as a monomer or modifying agent in the synthesis of specialized polymers with tailored properties.

Basic Information

Product Name	2-Methylpropanal Trimethylene Acetal
CAS No.	5702-49-8
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	Isobutyraldehyde Trimethylene Acetal; 1,3-Dioxane, 2-(2-Methylpropyl)-; 2-(2-Methylpropyl)-1,3-dioxane; Isobutylaldehyde Cyclic Propylene Acetal; Trimethylene Acetal of Isobutyraldehyde; 2-Isobutyl-1,3-dioxane
EINECS	Contact for details

Quality Control

Our 2-Methylpropanal Trimethylene Acetal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including Certificates of Analysis (COA) with detailed chromatographic profiles for each shipment. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.410 - 1.415
Density (g/mL, 20°C)	0.92 - 0.96

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.