Description

4-(Methylphenyl)Sulfonylacetonitrile is a versatile organic intermediate featuring a sulfonyl-activated methylene group adjacent to a nitrile functionality. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. Industries that require this product include pharmaceutical development for creating active ingredients, agrochemical manufacturing for novel crop protection agents, and academic or industrial R&D laboratories for organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides.
• Organic Synthesis Building Block: Employed in Knoevenagel condensations and other C-C bond-forming reactions to create complex heterocycles and fine chemicals.
• Material Science Research: Serves as a monomer or modifier in the development of specialty polymers and advanced materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized colorants.

Basic Information

Product Name	4-(Methylphenyl)Sulfonylacetonitrile
CAS No.	5697-44-9
Molecular Formula	C9H9NO2S
Molecular Weight	195.24 g/mol
Synonyms	p-Toluenesulfonylacetonitrile; (4-Methylphenyl)sulfonylacetonitrile; 4-Methylbenzenesulfonylacetonitrile; Tosylacetonitrile; TSAN; 2-[(4-Methylphenyl)sulfonyl]acetonitrile; α-(p-Toluenesulfonyl)acetonitrile; Acetonitrile, [(4-methylphenyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our 4-(Methylphenyl)Sulfonylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, protect from moisture and store under an inert atmosphere if the container is opened frequently.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.