Description

2-Cyclopropylideneacetic Acid is a versatile and reactive organic building block characterized by its cyclopropylidene moiety and carboxylic acid functionality. This compound matters as a key synthetic intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, especially those containing strained ring systems for enhanced biological activity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its reactive structure to create compounds with specific modes of action.
• Organic Synthesis Building Block: Employed in cyclopropanation reactions, Michael additions, and other C-C bond-forming processes to construct complex organic molecules.
• Material Science Research: Investigated as a monomer or cross-linking agent for the development of novel polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-Cyclopropylideneacetic Acid
CAS No.	5687-73-0
Molecular Formula	C5H6O2
Molecular Weight	98.10 g/mol
Synonyms	2-Cyclopropylideneacetic Acid; Cyclopropylideneacetic Acid; (Cyclopropylidene)acetic Acid; 2-(Cyclopropylidene)acetic Acid; 3-Cyclopropylidenepropanoic Acid; NSC 163022; 2-(Cyclopropylmethylidene)acetic acid
EINECS	227-137-5

Quality Control

Our 2-Cyclopropylideneacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.