Description

2-Amino-2-Cyclopropylpropionic Acid is a non-proteinogenic amino acid derivative featuring a cyclopropyl side chain, which imparts unique conformational rigidity and metabolic stability. This compound is a versatile chiral building block of significant interest in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and central nervous system (CNS) drug candidates.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational constraints into peptide backbones, enhancing metabolic stability, bioavailability, and receptor selectivity.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators with improved efficacy.
• Ligand & Catalyst Development: Employed in the design of chiral ligands and organocatalysts for asymmetric synthesis.
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies and metabolic pathway investigations.
• Material Science: Potential monomer for synthesizing specialized polymers with unique thermal and mechanical properties.

Basic Information

Product Name	2-Amino-2-Cyclopropylpropionic Acid
CAS No.	5687-72-9
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	2-Cyclopropylalanine; (2R/S)-2-Amino-2-cyclopropylpropanoic Acid; α-Amino-α-cyclopropylpropionic Acid; DL-2-Cyclopropylalanine; 2-Amino-2-cyclopropylpropanoic Acid; Cyclopropylalanine; NSC 163022; (±)-2-Amino-2-cyclopropylpropionic Acid
EINECS	227-138-9

Quality Control

Our 2-Amino-2-Cyclopropylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and impurities is available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.