Description

Cyclopropyl-(3-Nitro-Phenyl)-Methanone is a specialized organic building block featuring a cyclopropyl ketone moiety attached to a nitro-substituted phenyl ring. This unique molecular architecture makes it a valuable intermediate for synthesizing more complex chemical entities, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and agrochemical discovery. The compound's structure is pivotal for introducing conformational constraint and specific pharmacophores into target molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Building Block: Used to introduce the cyclopropyl and nitro-phenyl motifs into lead compounds during structure-activity relationship (SAR) studies to modulate potency, selectivity, and metabolic stability.
• Agrochemical Research: Serves as an intermediate in the synthesis of experimental herbicides, fungicides, and insecticides, where the cyclopropyl group can enhance biological activity.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials requiring specific light-absorbing or electronic properties.
• Chemical Synthesis Reference Standard: Used as a pure standard for analytical method development, quality control, and spectroscopic calibration in laboratory settings.

Basic Information

Product Name	Cyclopropyl-(3-Nitro-Phenyl)-Methanone
CAS No.	5680-51-3
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	3-Nitrobenzoylcyclopropane; 1-Cyclopropyl-3'-nitrophenylmethanone; (3-Nitrophenyl)(cyclopropyl)methanone; Cyclopropyl 3-Nitrophenyl Ketone; 3'-Nitrocyclopropylphenylketone; 3-Nitrobenzoic acid cyclopropyl ester (ketone form); NSC 406911
EINECS	Contact for details

Quality Control

Our Cyclopropyl-(3-Nitro-Phenyl)-Methanone is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.