Description

2-Chloro-4-Nitrobenzaldehyde is a versatile aromatic aldehyde derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of its chloro and nitro substituents, which enable selective functionalization for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing benzimidazole or quinazoline cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the nitro and aldehyde groups allow for further cyclization and derivatization.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants, contributing to the chromophore structure.
• Ligand and Catalyst Development: Employed in academic and industrial research to create novel chelating ligands for metal catalysis and coordination chemistry.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with specific thermal or optical properties.
• Organic Synthesis Research: A valuable reagent for methodologies like nucleophilic aromatic substitution (SNAr) and reductive amination in process chemistry and scale-up studies.

Basic Information

Item	Detail
Product Name	2-Chloro-4-Nitrobenzaldehyde
CAS No.	5568-33-2
Molecular Formula	C7H4ClNO3
Molecular Weight	185.56 g/mol
Synonyms	4-Nitro-2-chlorobenzaldehyde; 2-Chloro-4-nitrobenzenecarboxaldehyde; o-Chloro-p-nitrobenzaldehyde; 2-Chloro-4-nitro-benzaldehyde; Benzaldehyde, 2-chloro-4-nitro-; NSC 403119; 2-Chloro-4-nitrobenzaldehyde (technical grade)
EINECS	226-933-5

Quality Control

Our 2-Chloro-4-Nitrobenzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	72 - 76 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.