Description

2-(2-Chloro-1-Methylethoxy)-1,3,2-Dioxaphospholane is a specialized organophosphorus compound, specifically a cyclic phosphite ester derivative, that serves as a crucial intermediate in advanced chemical synthesis. Its primary value lies in its bifunctional reactivity, featuring both a cyclic phosphite and a chlorinated side chain, making it a versatile building block for creating complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleotide analogs, prodrugs, and other bioactive molecules with potential therapeutic applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific phosphorus-containing scaffolds.
• Polymer Chemistry: Acts as a monomer or co-monomer for creating specialty polymers, including flame retardants, stabilizers, and materials with tailored surface properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel phosphorus-based ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating libraries of compounds in medicinal and materials chemistry.
• Surface Modification Agent: Can be utilized to functionalize surfaces or nanoparticles, imparting specific chemical properties for advanced material applications.

Basic Information

Item	Detail
Product Name	2-(2-Chloro-1-Methylethoxy)-1,3,2-Dioxaphospholane
CAS No.	5559-69-3
Molecular Formula	C5H10ClO3P
Molecular Weight	184.56 g/mol
Synonyms	2-(2-Chloro-1-methylethoxy)-1,3,2-dioxaphospholane; 2-(2-Chloroisopropoxy)-1,3,2-dioxaphospholane; 2-Chloro-1-methylethyl ethylene phosphite; 1,3,2-Dioxaphospholane, 2-(2-chloro-1-methylethoxy)-; Ethylene 2-chloro-1-methylethyl phosphite; 2-(2-Chloropropoxy)-1,3,2-dioxaphospholane; Chloromethyl ethylene phosphite derivative
EINECS	226-904-6

Quality Control

Our production of 2-(2-Chloro-1-Methylethoxy)-1,3,2-Dioxaphospholane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing specific results for purity, moisture content, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.