Description

2,4,4,4-Tetrafluorobutyronitrile is a specialized fluorinated nitrile compound, identified by CAS NO 5522-59-8, valued for its unique reactivity as a versatile building block in advanced chemical synthesis. Its molecular structure, featuring multiple fluorine atoms, makes it a critical intermediate for introducing fluorinated moieties into target molecules, enhancing their properties. This high-value chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel compounds with improved metabolic stability, lipophilicity, or material characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key fluorinated synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing trifluoromethyl or difluoroalkyl groups.
• Agrochemical Synthesis: Used in creating novel herbicides, insecticides, and fungicides where fluorination can improve biological activity and environmental persistence.
• Advanced Material Precursor: Acts as a monomer or building block for synthesizing specialty polymers, liquid crystals, and electronic materials with specific dielectric or surface properties.
• Organic Synthesis Reagent: Employed in nucleophilic addition and cyclization reactions to construct complex, fluorinated heterocycles and aliphatic chains in fine chemical production.
• Fluorine Chemistry Research: A valuable compound for academic and industrial R&D focused on exploring new methodologies in fluorination and the synthesis of organofluorine compounds.

Basic Information

Product Name	2,4,4,4-Tetrafluorobutyronitrile
CAS No.	5522-59-8
Molecular Formula	C4H3F4N
Molecular Weight	141.07 g/mol
Synonyms	2,4,4,4-Tetrafluorobutanenitrile; Perfluorobutyronitrile; Tetrafluorobutyronitrile; 4,4,4-Trifluoro-3-(trifluoromethyl)propionitrile; Butyronitrile, 2,4,4,4-tetrafluoro-; 3,3,3-Trifluoro-2-(trifluoromethyl)propionitrile
EINECS	226-852-1

Quality Control

Our 2,4,4,4-Tetrafluorobutyronitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.4 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.