Description

Andrographolide is a labdane diterpenoid lactone compound, recognized as the primary bioactive constituent of the medicinal plant Andrographis paniculata. This compound matters for its significant pharmacological properties, including potent anti-inflammatory, antiviral, and immunomodulatory activities. It is needed by manufacturers in the pharmaceutical, nutraceutical, and research sectors for developing therapeutic formulations and conducting advanced biomedical studies.

Application

• Pharmaceutical Intermediates: Serves as a key active pharmaceutical ingredient (API) or starting material for anti-inflammatory, antiviral, and hepatoprotective drugs.
• Dietary Supplements & Nutraceuticals: Formulated into capsules, tablets, and liquid extracts to support immune system function and overall wellness.
• Clinical & Biomedical Research: Used as a reference standard and investigational compound in studies targeting cancer, infectious diseases, and metabolic disorders.
• Traditional & Herbal Medicine: Incorporated into standardized herbal preparations where the therapeutic benefits of Andrographis paniculata are desired.
• Cosmeceuticals: Explored for inclusion in topical formulations for its potential anti-inflammatory and skin-soothing properties.
• Veterinary Applications: Used in animal health products aimed at boosting immunity and managing infections.

Basic Information

Product Name	Andrographolide
CAS No.	5508-58-7
Molecular Formula	C20H30O5
Molecular Weight	350.45 g/mol
Synonyms	3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Andrographis; Andrographolid; Andrographis extract; 14-Deoxy-11,12-didehydroandrographolide (related compound); Kalmegh; Green Chiretta extract; King of Bitters extract; Labdane diterpene lactone
EINECS	226-852-5

Quality Control

Our Andrographolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification, to ensure it meets high-grade specifications suitable for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Microbial Limits	Complies with USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.