Description

1,2-Diiodo-3,4,5,6-tetramethylbenzene is a highly functionalized, multi-substituted aromatic compound that serves as a valuable synthetic intermediate and building block in advanced organic chemistry. Its unique structure, featuring two iodine atoms on a heavily methylated benzene ring, makes it a versatile precursor for cross-coupling reactions and the synthesis of complex molecular architectures. This specialty chemical is primarily utilized by research institutions and industrial R&D departments focused on developing novel materials, pharmaceuticals, and ligands for catalysis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly where sterically hindered aromatic systems are required.
• Organic Synthesis & Research: Acts as a versatile precursor in cross-coupling reactions (e.g., Suzuki, Stille, Negishi) for creating novel organic compounds and functional materials in academic and industrial R&D settings.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysts, exploiting the electron-donating properties of the methyl groups and the reactivity of the iodine atoms.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and other advanced materials where controlled molecular geometry and electronic properties are critical.
• Agrochemical Research: Functions as an intermediate in the development of new crop protection agents and herbicides with tailored biological activity.

Basic Information

Product Name	1,2-Diiodo-3,4,5,6-tetramethylbenzene
CAS No.	5503-82-2
Molecular Formula	C10H12I2
Molecular Weight	393.99 g/mol
Synonyms	1,2-Diiodo-3,4,5,6-tetramethylbenzene; 3,4,5,6-Tetramethyl-1,2-diiodobenzene; 1,2-Diiodo-3,4,5,6-tetramethyl-benzene; Durene, 1,2-diiodo-; Benzene, 1,2-diiodo-3,4,5,6-tetramethyl-; 1,2-Diiododurene
EINECS	Contact for details

Quality Control

Our production of 1,2-Diiodo-3,4,5,6-tetramethylbenzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.