Description

4-Bromophenylboronic Acid is a versatile and high-value organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for creating biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific bromo-substituted phenyl groups.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	4-Bromophenylboronic Acid
CAS No.	5467-74-3
Molecular Formula	C6H6BBrO2
Molecular Weight	200.83 g/mol
Synonyms	(4-Bromophenyl)boronic Acid; p-Bromophenylboronic Acid; B-(4-Bromophenyl)boronic Acid; 4-BromoBenzeneboronic Acid; 4-Bromobenzeneboronic Acid; Boronic acid, B-(4-bromophenyl)-; 5467-74-3; NSC 168102
EINECS	226-763-5

Quality Control

Our 4-Bromophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for prolonged use to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%
Melting Point	250-255°C (dec.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.