Description

Benzeneacetic Acid, A-(1-Hydroxycyclobutyl)- is a specialized organic compound featuring a phenylacetic acid core substituted with a hydroxycyclobutyl group. This unique structure makes it a valuable versatile chiral building block and intermediate for complex organic synthesis. It is primarily sought after by pharmaceutical research and development teams for the creation of novel active pharmaceutical ingredients (APIs) and fine chemical manufacturers.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in medicinal chemistry programs.
• Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex molecules in agrochemical, fragrance, and advanced material research.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in studies exploring new catalytic methodologies due to its defined stereochemistry.
• Academic & Industrial R&D: Employed in chemical libraries and for method development in synthetic organic chemistry laboratories worldwide.

Basic Information

Product Name	Benzeneacetic Acid, A-(1-Hydroxycyclobutyl)-
CAS No.	5463-97-8
Molecular Formula	C₁₂H₁₄O₃
Molecular Weight	206.24 g/mol
Synonyms	α-(1-Hydroxycyclobutyl)phenylacetic Acid; 2-(1-Hydroxycyclobutyl)-2-phenylacetic Acid; (1-Hydroxycyclobutyl)(phenyl)acetic Acid; Phenylacetic Acid, α-(1-Hydroxycyclobutyl)-; (RS)-α-(1-Hydroxycyclobutyl)benzeneacetic Acid; Cyclobutanol, 1-(carboxyphenylmethyl)-; 5463-97-8; (1-Hydroxycyclobutyl)(phenyl)ethanoic Acid
EINECS	Contact for details

Quality Control

Every batch of our Benzeneacetic Acid, A-(1-Hydroxycyclobutyl)- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.