Description

n-Butyl Cyanoacetate is a versatile organic ester widely used as a key synthetic intermediate in fine chemical and pharmaceutical manufacturing. Its value lies in its bifunctional cyano and ester groups, which enable its use in condensation reactions, particularly in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs). This product is essential for R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-purity building blocks.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various heterocyclic compounds, including pyrimidines and pyridines, which are core structures in many APIs.
• Agrochemical Synthesis: Used in the production of pesticides and herbicides, where it serves as a precursor for molecules with specific biological activity.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and colorants.
• Polymer Modification: Employed in the synthesis of specialty monomers or as a modifier to introduce cyano functionalities into polymer chains.
• Chemical Research & Development: A valuable reagent for organic synthesis, particularly in Knoevenagel condensation reactions to form α,β-unsaturated nitriles and esters.
• Flavor and Fragrance Ingredient Synthesis: Used as a precursor in the creation of certain aroma chemicals and flavor compounds.

Basic Information

Product Name	n-Butyl Cyanoacetate
CAS No.	5459-58-5
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	Butyl Cyanoacetate; Cyanoacetic Acid Butyl Ester; n-Butyl Cyanoethanoate; Butyl 2-Cyanoacetate; Cyanoacetic Acid n-Butyl Ester; NSC 4011; 2-Cyanoacetic Acid Butyl Ester
EINECS	226-719-8

Quality Control

Our n-Butyl Cyanoacetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.422 - 1.426
Density (20°C)	0.98 - 1.02 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.