Description

2-Hydroxyethylacetoacetate is a versatile bifunctional ester and a key chemical intermediate prized for its reactive hydroxyl and acetoacetate groups. This compound matters for its ability to act as a building block in organic synthesis, enabling the creation of complex molecules for high-value applications. Industries such as pharmaceuticals, agrochemicals, and specialty polymers rely on it for synthesizing active ingredients, UV absorbers, and cross-linking agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring acetoacetate or β-ketoester functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where it serves as a core building block for active molecules.
• Polymer & Resin Modifier: Functions as a reactive diluent or cross-linking agent in specialty polymer formulations, including coatings, adhesives, and UV-curable resins.
• Chemical Synthesis Reagent: Employed in organic synthesis for Claisen condensations and as a source of the acetoacetate group in heterocyclic chemistry.
• UV Absorber Production: Acts as an intermediate in the manufacture of benzophenone and other types of ultraviolet light stabilizers for plastics and coatings.
• Flavor & Fragrance Ingredient: Used in the synthesis of certain aroma chemicals and flavoring agents due to its ester structure.

Basic Information

Product Name	2-Hydroxyethylacetoacetate
CAS No.	5459-04-1
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	Acetoacetic Acid 2-Hydroxyethyl Ester; Ethylene Glycol Monoacetoacetate; 2-(Acetoacetoxy)ethanol; Glycol Monoacetoacetate; HEAA; β-Acetoxy-γ-butyrolactone (related form); Ethanol, 2-(acetoacetoxy)-; 1-Hydroxy-2-acetoacetoxyethane
EINECS	226-722-4

Quality Control

Our 2-Hydroxyethylacetoacetate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including assay, identity confirmation, and impurity profiling, to ensure it meets precise specifications for industrial and fine chemical use. A Certificate of Analysis (COA) detailing purity, physical properties, and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.435 - 1.445
Density (20°C)	1.10 - 1.20 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.