Description

Methyl 5-Bromovalerate CAS NO 5454-83-1 is a versatile brominated ester building block, essential for introducing the 5-bromopentyl moiety into target molecules. Its primary value lies in its reactivity as an alkylating agent and as a key intermediate in multi-step organic synthesis, enabling the construction of complex chemical architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug discovery to material science.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a functionalized alkyl chain linker.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized phosphine ligands or metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce bromoalkyl side chains into polymers for subsequent functionalization or to create flame-retardant materials.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, to form carbon-carbon bonds.
• Nucleoside and Peptide Modification: Useful for the alkylation of nucleosides, nucleotides, or amino acids in medicinal chemistry programs.
• Flavor and Fragrance Industry: Potential intermediate in the synthesis of specific ester-based aroma compounds.
• Organic Synthesis Building Block: Fundamental reagent for homologation reactions and the preparation of ω-bromo acids, aldehydes, and other derivatives.

Basic Information

Product Name	Methyl 5-Bromovalerate
CAS No.	5454-83-1
Molecular Formula	C6H11BrO2
Molecular Weight	195.06 g/mol
Synonyms	5-Bromovaleric Acid Methyl Ester; Methyl 5-Bromopentanoate; Pentanoic Acid, 5-Bromo-, Methyl Ester; Methyl δ-Bromovalerate; 5-Bromopentanoic Acid Methyl Ester; Methyl Ester of 5-Bromovaleric Acid; δ-Bromovaleric Acid Methyl Ester; Bromovaleric Acid Methyl Ester
EINECS	226-704-5

Quality Control

Our Methyl 5-Bromovalerate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its sensitivity to light and potential reactivity, it is recommended to store under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4580 - 1.4620
Density (g/mL at 20°C)	1.38 - 1.42

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.