Description

Ethyl 4-Nitrophenylacetate is a versatile organic ester compound, serving as a key synthetic intermediate in fine chemical and pharmaceutical manufacturing. Its value lies in the reactive nitro and ester functional groups, which allow for selective transformations into more complex molecules. This product is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing aniline or phenylacetic acid derivatives.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a protected or activated form of 4-nitrophenylacetic acid for peptide coupling, esterification, and other coupling reactions.
• Chemical Research & Development: A valuable substrate for method development in catalysis, green chemistry, and novel synthetic route exploration.
• Dye & Pigment Precursor: Utilized in the synthesis of complex organic dyes and colorants due to the nitro aromatic structure.
• Biochemical Probe Synthesis: Employed in creating enzyme substrates or fluorescent tags for diagnostic and research applications.

Basic Information

Product Name	Ethyl 4-Nitrophenylacetate
CAS No.	5445-26-1
Molecular Formula	C10H11NO4
Molecular Weight	209.20 g/mol
Synonyms	4-Nitrophenylacetic Acid Ethyl Ester; Ethyl (4-Nitrophenyl)acetate; Ethyl p-Nitrophenylacetate; p-Nitrophenylacetic Acid Ethyl Ester; (4-Nitrophenyl)acetic Acid Ethyl Ester; Acetic acid, (4-nitrophenyl)-, ethyl ester; Ethyl 4-Nitrobenzeneacetate
EINECS	226-637-9

Quality Control

Our Ethyl 4-Nitrophenylacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.