Description

4-Hydroxybenzhydrazide is a versatile aromatic hydrazide derivative with significant utility as a key synthetic intermediate and analytical reagent. Its core value lies in its bifunctional structure, featuring both a phenolic hydroxyl group and a reactive hydrazide moiety, enabling its use in the creation of complex heterocyclic compounds and as a selective chelating agent. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in developing new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various heterocyclic compounds with potential biological activity, including hydrazones and azoles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chelating Agent & Metal Ion Analysis: Serves as a selective ligand for the complexometric determination and separation of specific transition metal ions in analytical chemistry.
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialty polymers, such as polyhydrazides and polyoxadiazoles, for high-performance materials.
• Corrosion Inhibitor Formulation: Incorporated into formulations designed to protect metal surfaces in industrial processes.
• Chemical Research & Development: A valuable reagent for organic synthesis, particularly in condensation reactions and the formation of carbon-nitrogen bonds.

Basic Information

Product Name	4-Hydroxybenzhydrazide
CAS No.	5351-23-5
Molecular Formula	C7H8N2O2
Molecular Weight	152.15 g/mol
Synonyms	p-Hydroxybenzhydrazide; 4-Hydroxybenzohydrazide; p-Hydroxybenzohydrazide; (4-Hydroxybenzoyl)hydrazine; Salicylhydrazide (Note: This is a common misnomer; salicylhydrazide is 2-hydroxybenzohydrazide); Benzoic acid, 4-hydroxy-, hydrazide; 1-(4-Hydroxybenzoyl)hydrazine
EINECS	226-304-9

Quality Control

Our 4-Hydroxybenzhydrazide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	258 - 262 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.