Description

2-Bromo-5-(tert-Butyl)-1,3-Dimethylbenzene is a high-purity brominated aromatic compound that serves as a versatile and valuable intermediate in advanced organic synthesis. Its molecular structure, featuring a bromine atom and a sterically hindered tert-butyl group on a dimethylbenzene backbone, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to introduce specific functional groups and modulate the physical and biological characteristics of target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a sterically hindered aromatic moiety.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the bromine atom facilitates further cross-coupling reactions.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers with specific aromatic architectures.
• Fine Chemical Production: Acts as a starting material for the manufacture of dyes, pigments, and other high-value specialty chemicals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	2-Bromo-5-(tert-Butyl)-1,3-Dimethylbenzene
CAS No.	5345-05-1
Molecular Formula	C12H17Br
Molecular Weight	241.17 g/mol
Synonyms	1-Bromo-4-tert-butyl-2,6-dimethylbenzene; 2,6-Dimethyl-4-tert-butylbromobenzene; 4-tert-Butyl-2,6-dimethylbromobenzene; 4-(tert-Butyl)-2,6-dimethylbromobenzene; 2-Bromo-1,3-dimethyl-5-tert-butylbenzene; 5-tert-Butyl-2-bromo-1,3-dimethylbenzene; Bromomesitylene, 4-tert-butyl derivative
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(tert-Butyl)-1,3-Dimethylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material is suitable for demanding applications in GMP-compliant pharmaceutical synthesis and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.