Description

[1R-(Endo,Anti)]-3-Bromo-2-Oxobornane-8-Sulphonic Acid is a high-purity, stereochemically defined chiral building block derived from camphor. This compound is valued for its rigid, polycyclic structure and the presence of multiple functional handles, making it a versatile intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory drugs.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Advanced Organic Synthesis: Serves as a rigid scaffold for constructing complex natural product analogs and other structurally intricate compounds in academic and industrial research.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals, flavors, and fragrances where precise stereochemistry is critical.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific chiral or structural properties.

Basic Information

Product Name	[1R-(Endo,Anti)]-3-Bromo-2-Oxobornane-8-Sulphonic Acid
CAS No.	5344-58-1
Molecular Formula	C10H13BrO4S
Molecular Weight	309.18 g/mol
Synonyms	3-Bromo-2-oxobornane-8-sulfonic acid, (1R,2S,4R)-3-Bromo-1,7,7-trimethylbicyclo[2.2.1]heptane-2-one-8-sulfonic acid, 3-Bromocamphor-8-sulfonic acid, 8-Sulfocamphor-3-bromide, (1R)-3-Bromo-2-oxobornane-8-sulfonic acid, endo-3-Bromo-2-oxobornane-8-sulphonic acid, BCSA
EINECS	226-292-6

Quality Control

Our [1R-(Endo,Anti)]-3-Bromo-2-Oxobornane-8-Sulphonic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, chemical assay, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after initial use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.