Description

2',4',6',β-Tetramethylbutyrophenone CAS NO 5344-18-3 is a specialized aromatic ketone derivative, valued for its unique sterically hindered molecular structure. This compound serves as a critical intermediate and building block in advanced organic synthesis, enabling the production of high-performance materials and fine chemicals. It is essential for research and development laboratories, pharmaceutical manufacturers, and industrial chemical producers seeking to develop novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules.
• Photoinitiator Component: Used in the formulation of UV-curable inks, coatings, and adhesives due to its ketone functionality.
• Organic Synthesis Reagent: Acts as a precursor or intermediate in Grignard reactions, Friedel-Crafts acylations, and other sterically demanding transformations.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials.
• Flavor and Fragrance Synthesis: Intermediate for creating specific musk or aromatic compounds used in perfumery.

Basic Information

Product Name	2',4',6',β-Tetramethylbutyrophenone
CAS No.	5344-18-3
Molecular Formula	C14H20O
Molecular Weight	204.31 g/mol
Synonyms	2,4,6-Trimethyl-β,β-dimethylpropiophenone; 2,4,6-Trimethyl-3,3-dimethylpropiophenone; 1-(2,4,6-Trimethylphenyl)-3,3-dimethylbutan-1-one; 3,3-Dimethyl-1-(2,4,6-trimethylphenyl)-1-butanone; Butyrophenone, 2',4',6'-trimethyl-3,3-dimethyl-; Tetramethylbutyrophenone; TMDP
EINECS	226-294-6

Quality Control

Our 2',4',6',β-Tetramethylbutyrophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.