Description

3-(Tetrahydrofuran-2-Ylmethoxy)Propanenitrile is a versatile nitrile-functionalized ether compound that serves as a valuable building block in advanced organic synthesis. Its molecular structure, featuring both a tetrahydrofuran ring and a reactive nitrile group, makes it a critical intermediate for constructing complex molecules with specific functionalities. This high-purity chemical is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors seeking reliable and scalable intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring ether-linked nitrile moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where its structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed as a functional monomer or cross-linking agent to introduce polar nitrile groups into polymer backbones, enhancing material properties.
• Fine Chemical Production: Integral to multi-step synthetic routes for flavors, fragrances, and other high-value specialty chemicals.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reaction methodologies and constructing novel heterocyclic compounds.

Basic Information

Product Name	3-(Tetrahydrofuran-2-Ylmethoxy)Propanenitrile
CAS No.	5338-10-3
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	2-(2-Cyanoethoxy)methyltetrahydrofuran; 3-[(Tetrahydro-2-furanyl)methoxy]propanenitrile; Tetrahydrofurfuryloxypropionitrile; 3-(Tetrahydrofurfuryloxy)propionitrile; THF-2-ylmethoxy propanenitrile; Propanenitrile, 3-[(tetrahydro-2-furanyl)methoxy]-; (Tetrahydrofuran-2-ylmethoxy)acetonitrile homologue
EINECS	226-259-7

Quality Control

Our 3-(Tetrahydrofuran-2-Ylmethoxy)Propanenitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.450 - 1.455
Density (g/mL at 20°C)	1.02 - 1.06

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.