Description

tert-Butyl Bromoacetate is a versatile alkylating agent and a key organic synthesis intermediate. This compound is valued for its role as a tert-butoxycarbonyl (Boc) protected bromoacetyl synthon, enabling the introduction of reactive bromoacetyl groups under mild conditions. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active pharmaceutical ingredients (APIs), complex molecules, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the construction of peptide mimetics and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the bromoacetyl moiety is required.
• Peptide Chemistry: Serves as a reagent for the selective modification of peptides and proteins, facilitating the attachment of labels, tags, or other functional groups.
• Polymer & Material Science: Employed as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Reagent: A valuable electrophile in alkylation reactions, nucleophilic substitutions, and for the preparation of more complex esters and ketones.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	tert-Butyl Bromoacetate
CAS No.	5292-43-3
Molecular Formula	C6H11BrO2
Molecular Weight	195.06 g/mol
Synonyms	Bromoacetic Acid tert-Butyl Ester; 2-Bromoacetic Acid 1,1-Dimethylethyl Ester; t-Butyl Bromoacetate; tert-Butyl 2-bromoacetate; Bromoacetic Acid t-Butyl Ester; (CH3)3COCOCH2Br; 1,1-Dimethylethyl bromoacetate
EINECS	226-124-8

Quality Control

Our tert-Butyl Bromoacetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4430 - 1.4470
Density (g/mL at 20°C)	1.28 - 1.32

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.