Description

Diethyl 2-(4-Chloroanilino)Malonate is a high-purity organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a versatile building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing quinoline, pyrimidine, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and insecticides, leveraging the 4-chloroanilino moiety.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing complex organic dyes and pigments, where its malonate ester group allows for further functionalization.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities for screening.
• Fine Chemical Production: Employed in the multi-step synthesis of various fine chemicals and specialty materials requiring precise molecular architecture.

Basic Information

Product Name	Diethyl 2-(4-Chloroanilino)Malonate
CAS No.	5203-01-0
Molecular Formula	C13H16ClNO4
Molecular Weight	285.72 g/mol
Synonyms	Diethyl (4-chlorophenylamino)malonate; 2-(4-Chloroanilino)malonic Acid Diethyl Ester; Diethyl (p-chloroanilino)malonate; Malonic acid, (4-chloroanilino)-, diethyl ester; 4-Chloro-N-(diethoxycarbonylmethyl)aniline; Diethyl 2-[(4-chlorophenyl)amino]propanedioate; Propanedioic acid, 2-[(4-chlorophenyl)amino]-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-(4-Chloroanilino)Malonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee compliance with your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.