Description

1-Azabicyclo[2.2.2]octane-3-carboxaldehyde is a versatile bicyclic organic compound featuring a quinuclidine core with an aldehyde functional group. This structure makes it a valuable and highly sought-after advanced pharmaceutical intermediate and a key chiral building block in organic synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug molecules, particularly those targeting the nervous system.
• Agrochemical Synthesis: Used as a building block for developing novel pesticides and herbicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a core structure for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D: Employed in chemical research for studying reaction mechanisms and developing new synthetic methodologies.
• Fine Chemical Production: Integral to the manufacture of high-value, complex specialty chemicals for various industrial applications.

Basic Information

Product Name	1-Azabicyclo[2.2.2]octane-3-carboxaldehyde
CAS No.	5176-21-6
Molecular Formula	C8H13NO
Molecular Weight	139.19 g/mol
Synonyms	3-Formylquinuclidine; Quinuclidine-3-carboxaldehyde; 3-Quinuclidinecarboxaldehyde; 1-Azabicyclo[2.2.2]octane-3-carbaldehyde; 3-Carboxyaldehydequinuclidine; 3-Quinuclidyl aldehyde; 1-Azabicyclo(2.2.2)octane-3-carboxaldehyde
EINECS	225-943-7

Quality Control

Our 1-Azabicyclo[2.2.2]octane-3-carboxaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.