Description

1-Chloro-4-(Phenylethynyl)Benzene is a high-purity organic building block characterized by its halogenated aromatic structure and terminal alkyne functionality. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in cross-coupling reactions and polymer synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where its structural motif contributes to biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions to form conjugated systems.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new synthetic pathways.
• Ligand Precursor: Can be used to synthesize specialized ligands for catalysis and coordination chemistry.

Basic Information

Product Name	1-Chloro-4-(Phenylethynyl)Benzene (98%)
CAS No.	5172-02-1
Molecular Formula	C14H9Cl
Molecular Weight	212.67 g/mol
Synonyms	4-Chlorodiphenylacetylene; 1-Chloro-4-(phenylethynyl)benzene; p-Chlorodiphenylacetylene; 4-(Phenylethynyl)chlorobenzene; (4-Chlorophenyl)(phenyl)acetylene; NSC 406913; 4-Chloro-1-(phenylethynyl)benzene
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-(Phenylethynyl)Benzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure the specified purity of 98% minimum and confirm identity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.