Description

Ethanone, 2,2-Dichloro-1-(4-Fluorophenyl)- (9Ci) is a specialized halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a versatile precursor for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by R&D chemists and process development scientists working on the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals where the introduction of a dichloroacetyl moiety onto a fluorinated aromatic ring is required.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the halogenated aromatic system.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle or labeling agent in the study of biological pathways and protein interactions.
• Academic & Industrial R&D: Employed in methodological studies and as a benchmark compound in catalysis and new synthetic route development.

Basic Information

Product Name	Ethanone, 2,2-Dichloro-1-(4-Fluorophenyl)- (9Ci)
CAS No.	5157-58-4
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	2,2-Dichloro-1-(4-fluorophenyl)ethanone; 4-Fluorophenyldichloroacetyl; 1-(4-Fluorophenyl)-2,2-dichloroethanone; 4'-Fluoro-2,2-dichloroacetophenone; p-Fluorophenyldichloroacetyl; α,α-Dichloro-4-fluoroacetophenone; Dichloro(4-fluorophenyl)methanone; CAS 5157-58-4
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2-Dichloro-1-(4-Fluorophenyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.