Description

2,2-Dichloro-1-(4-Chlorophenyl)Ethanone is a versatile chlorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in its reactive dichloroacetyl group and stable aromatic core, making it a key precursor for constructing complex molecules. This intermediate is primarily needed by the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with chlorinated aromatic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its chlorinated pattern contributes to biological activity.
• Chemical Research & Development: Serves as a key starting material in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and organic pigments due to its aromatic ketone functionality.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to form more complex biaryl structures.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	2,2-Dichloro-1-(4-Chlorophenyl)Ethanone
CAS No.	5157-57-3
Molecular Formula	C8H5Cl3O
Molecular Weight	223.48 g/mol
Synonyms	4'-Chloro-2,2-dichloroacetophenone; 2,2-Dichloro-1-(4-chlorophenyl)ethan-1-one; 1-(4-Chlorophenyl)-2,2-dichloroethanone; p-Chlorophenyldichloromethyl ketone; α,α-Dichloro-4-chloroacetophenone; NSC 406916; 4-Chloro-α,α-dichloroacetophenone
EINECS	225-923-9

Quality Control

Our 2,2-Dichloro-1-(4-Chlorophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.