Description

trans-4-Fluoro-β-Nitrostyrene is a high-purity fluorinated organic intermediate characterized by its distinct nitrovinyl and fluoroaryl functional groups. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the introduction of both fluorine and nitro-olefin motifs into target molecules. It is primarily sought by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the creation of fluorescent tags and activity-based probes for studying enzyme mechanisms and cellular processes.
• Organic Synthesis Building Block: Utilized in Michael addition reactions, cycloadditions, and other C-C bond-forming transformations to create complex molecular architectures.

Basic Information

Product Name	trans-4-Fluoro-β-Nitrostyrene
CAS No.	5153-69-5
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	(E)-1-Fluoro-4-(2-nitrovinyl)benzene; (E)-4-Fluoro-β-nitrostyrene; 4-Fluoro-trans-β-nitrostyrene; trans-1-Fluoro-4-(2-nitroethenyl)benzene; (E)-2-(4-Fluorophenyl)-1-nitroethene; 4-Fluoro-β-nitrostyrene; β-Nitro-4-fluorostyrene; 5153-69-5
EINECS	Contact for details

Quality Control

Our trans-4-Fluoro-β-Nitrostyrene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.